Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Male orgasmic disorder: comprehensive diagnostic and therapeutic approach from primary care with emphasis on the Latin American context. A narrative review
Trastorno orgásmico masculino: enfoque diagnóstico y terapéutico integral desde la atención primaria con énfasis en el contexto latinoamericano. Una revisión narrativa
1Department of Psychology and Health Sciences, Universidad a Distancia de Madrid (UDIMA), 28400 Madrid, Spain
2SERVIMED Clinical Research Center, University of Santander (UDES), 680002 Bucaramanga, Colombia
DOI: 10.22514/j.androl.2026.017 Vol.24,Issue 2,June 2026 pp.25-30
Submitted: 25 January 2026 Accepted: 28 April 2026
Published: 30 June 2026
*Corresponding Author(s): Mariajoseh Pereira Velásquez E-mail: BUC17181263@MAIL.UDES.EDU.CO
Male orgasmic disorder (MOD) is an underdiagnosed sexual dysfunction characterized by absence, delay, or significant reduction in orgasm following adequate stimulation, present in 75–100% of sexual encounters for a minimum of six months, with a global prevalence of 0.4–3% (1.6–2.8% in the Latin American population). Conceptual differentiation between orgasm and ejaculation is fundamental, as they represent separate neurophysiological processes that can dissociate pathologically. Multifactorial etiology includes organic components (endocrinopathies, neuropathies, pharmacological iatrogenesis: selective serotonin reuptake inhibitors (SSRIs) with odds ratio (OR) 7.0 for delayed ejaculation), psychological factors (performance anxiety, idiosyncratic masturbatory techniques, cognitive distortions), and relational factors (unresolved conflicts, loss of attraction). Primary care physicians play a crucial role in early detection through a structured evaluation protocol (directed sexological history, physical examination, selective laboratory workup: testosterone, prolactin, thyroid-stimulating hormone (TSH)). Effective therapeutic options include structured sexual psychotherapy (65–78% improvement), pharmacological modification (SSRI switch to bupropion: 58–72% resolution), couple therapy, and penile vibratory stimulation (72% orgasm recovery). A pragmatic diagnostic-therapeutic algorithm applicable in any primary care setting is proposed, with specific discussion of implementation challenges in Latin American health systems, particularly Colombia, Brazil, and Mexico.
Resumen
El trastorno orgásmico masculino (TOM) es una disfunción sexual infradiagnosticada caracterizada por la ausencia, el retraso o la reducción significativa del orgasmo tras una estimulación adecuada, presente en el 75–100% de los encuentros sexuales durante un mínimo de seis meses, con una prevalencia global del 0.4–3% (1.6–2.8% en la población latinoamericana). La diferenciación conceptual entre orgasmo y eyaculación es fundamental, ya que representan procesos neurofisiológicos distintos que pueden disociarse patológicamente. La etiología multifactorial incluye componentes orgánicos (endocrinopatías, neuropatías, iatrogenia farmacológica: inhibidores selectivos de la recaptación de serotonina (ISRS) con odds ratio (OR) 7.0 para eyaculación retardada), factores psicológicos (ansiedad de desempeño, técnicas de masturbación idiosincrásicas, distorsiones cognitivas) y factores relacionales (conflictos no resueltos, pérdida de atracción). Los médicos de atención primaria desempeñan un papel crucial en la detección precoz mediante un protocolo de evaluación estructurado (historia sexológica dirigida, exploración física, análisis de laboratorio selectivos: testosterona, prolactina, hormona estimulante de la tiroides (TSH)). Entre las opciones terapéuticas eficaces se incluyen la psicoterapia sexual estructurada (mejora del 65–78%), la modificación farmacológica (cambio de ISRS a bupropión: resolución del 58–72%), la terapia de pareja y la estimulación vibratoria del pene (recuperación del orgasmo en el 72%). Se propone un algoritmo diagnóstico-terapéutico pragmático aplicable en cualquier entorno de atención primaria, con un análisis específico de los desafíos de su implementación en los sistemas de salud latinoamericanos, en particular en Colombia, Brasil y México.
Sexual dysfunctions; Anorgasmia; Orgasm; Ejaculation; Diagnosis; Therapeutics; Primary care
Palabras Clave
Disfunciones sexuales; Anorgasmia; Orgasmo; Eyaculación; Diagnóstico; Terapéutica; Atención primaria
Mariajoseh Pereira Velásquez,Juan Sebastián Therán León. Male orgasmic disorder: comprehensive diagnostic and therapeutic approach from primary care with emphasis on the Latin American context. A narrative reviewTrastorno orgásmico masculino: enfoque diagnóstico y terapéutico integral desde la atención primaria con énfasis en el contexto latinoamericano. Una revisión narrativa. Revista Internacional de Andrología. 2026. 24(2);25-30.
[1] American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th edn. American Psychiatric Association: Arlington, VA. 2013.
[2] Alwaal A, Breyer BN, Lue TF. Normal male sexual function: emphasis on orgasm and ejaculation. Fertility and Sterility. 2015; 104: 1051–1060.
[3] Jenkins LC, Mulhall JP. Delayed orgasm and anorgasmia. Fertility and Sterility. 2015; 104: 1082–1088.
[4] Segraves RT. Considerations for a better definition of male orgasmic disorder in DSM V. The Journal of Sexual Medicine. 2010; 7: 690–695.
[5] Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, et al. An evidence-based unified definition of lifelong and acquired premature ejaculation: report of the second International Society for Sexual Medicine ad hoc committee for the definition of premature ejaculation. Sexual Medicine. 2014; 2: 41–59.
[6] Irfan M, Nik Hussain NH, Mohd Noor N, Mohamed M, Sidi H, Ismail SB. Epidemiology of male sexual dysfunction in Asian and European regions: a systematic review. American Journal of Men’s Health. 2020; 14: 1557988320937200.
[7] Briken P, Matthiesen S, Pietras L, Wiessner C, Klein V, Reed GM, et al. Estimating the prevalence of sexual dysfunction using ICD-11. Deutsches Ärzteblatt International. 2020; 117: 653–658.
[8] Laumann E, Nicolosi A, Glasser D, Paik A, Gingell C, Moreira E, et al. Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. International Journal of Impotence Research. 2005; 17: 39–57.
[9] Ferrari R. Writing narrative style literature reviews. Medical Writing. 2015; 24: 230–235.
[10] Pham MT, Rajić A, Greig JD, Sargeant JM, Papadopoulos A, McEwen SA. A scoping review of scoping reviews: advancing the approach and enhancing the consistency. Research Synthesis Methods. 2014; 5: 371–385.
[11] Zakhem GA, Goldberg JE, Motosko CC, Cohen BE, Ho RS. Sexual dysfunction in men taking systemic dermatologic medication: a systematic review. Journal of the American Academy of Dermatology. 2019; 81: 163–172.
[12] Jannini EA, Simonelli C, Lenzi A. Sexological approach to ejaculatory dysfunction. International Journal of Andrology. 2002; 25: 317–323.
[13] Carvalheira A, Santana R. Individual and relationship factors associated with the self-identified inability to experience orgasm in a community sample of heterosexual men from three European countries. Journal of Sex & Marital Therapy. 2016; 42: 257–266.
[14] Rosen RC, Heiman JR, Long JS, Fisher WA, Sand MS. Men with sexual problems and their partners: findings from the international survey of relationships. Archives of Sexual Behavior. 2016; 45: 159–173.
[15] Dubowitch E, Khurgin J. Cultural anorgasmia: considerations in the evaluation of male infertility in the Hasidic community. The Canadian Journal of Urology. 2019; 26: 9864–9866.
[16] McMahon CG, Jannini E, Waldinger M, Rowland D. Standard operating procedures in the disorders of orgasm and ejaculation. The Journal of Sexual Medicine. 2013; 10: 204–229.
[17] Corona G, Ricca V, Bandini E, Mannucci E, Lotti F, Boddi V, et al. Selective serotonin reuptake inhibitor-induced sexual dysfunction. The Journal of Sexual Medicine. 2009; 6: 1259–1269.
[18] Bala A, Nguyen HMT, Hellstrom WJG. Post-SSRI sexual dysfunction: a literature review. Sexual Medicine Reviews. 2018; 6: 29–34.
[19] Waldinger MD, Quinn P, Dilleen M, Mundayat R, Schweitzer DH, Boolell M. A multinational population survey of intravaginal ejaculation latency time. The Journal of Sexual Medicine. 2005; 2: 492–497.
[20] Althof SE, Rosen RC, Perelman MA, Rubio-Aurioles E. Standard operating procedures for taking a sexual history. The Journal of Sexual Medicine. 2013; 10: 26–35.
[21] Cabello Santamaría F. Manual of sexology and sexual therapy. 1st edn. Editorial Síntesis: Madrid. 2010.
[22] Corona G, Rastrelli G, Ricca V, Jannini EA, Vignozzi L, Monami M, et al. Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction. The Journal of Sexual Medicine. 2013; 10: 1074–1089.
[23] Incrocci L, Jensen PT. Pelvic radiotherapy and sexual function in men and women. The Journal of Sexual Medicine. 2013; 10: 53–64.
[24] Sánchez-Sánchez F, Ferrer-Casanova C, Ponce-Buj B, Sipán-Sarrión Y, Jurado-López AR, San Martin-Blanco C, et al. Design and validation of a male sexual function questionnaire. Medicina de Familia-Semergen. 2020; 46: 441–447. (In Spanish)
[25] Salonia A, Bettocchi C, Carvalho J, Corona G, Jones TH, Kadioglu A, et al.; European Association of Urology. Guidelines on sexual and reproductive health. 2024. Available at: https://uroweb.org/guidelines/sexual-and-reproductive-health (Accessed: 15 January 2026).
[26] Nelson CJ, Ahmed A, Valenzuela R, Parker M, Mulhall JP. Assessment of penile vibratory stimulation as a management strategy in men with secondary retarded orgasm. Urology. 2007; 69: 552–555, discussion 555–556.
[27] Rullo JE, Lorenz T, Ziegelmann MJ, Meihofer L, Herbenick D, Faubion SS. Genital vibration for sexual function and enhancement: a review of evidence. Sexual and Relationship Therapy. 2018; 33: 263–274.
[28] Wylie K, Hallam-Jones R, Harrington C. Psychological difficulties in patients with erectile dysfunction. Journal of Sex & Marital Therapy. 2004; 30: 321–331.
[29] Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997; 49: 822–830.
[30] Domes T, Najafabadi BT, Roberts M, Campbell J, Flannigan R, Bach P, et al. Canadian Urological Association guideline: erectile dysfunction. Canadian Urological Association Journal. 2021; 15: E489–E505.
[31] Rabinowitz MJ, Kohn TP, Ellimoottil C, Alam R, Liu JL, Herati AS. The impact of telemedicine on sexual medicine at a major academic center during the COVID-19 pandemic. Sexual Medicine. 2021; 9: 100366.
[32] Kim S, Cho MC, Cho SY, Chung H, Rajasekaran MR. Novel emerging therapies for erectile dysfunction. World Journal of Men’s Health. 2021; 39: 48–64.
[33] Hatzichristou D, Rosen RC, Derogatis LR, Low WY, Meuleman EJ, Sadovsky R, et al. Recommendations for the clinical evaluation of men and women with sexual dysfunction. The Journal of Sexual Medicine. 2010; 7: 337–348.
[34] Porst H, Burnett A, Brock G, Ghanem H, Giuliano F, Glina S, et al. SOP conservative (medical and mechanical) treatment of erectile dysfunction. The Journal of Sexual Medicine. 2013; 10: 130–171.
Top